Kit Lam Lab - UC Davis
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A novel high-throughput scanning microscope for label-free detection of protein and small-molecule chemical microarrays....

Yy, Fei Jp, Landry Ys, Sun Xd, Zhu Jt, Luo Xb, Wang Ks, Lam

Published in Review of Scientific Instruments

We describe a novel scanning optical microscope based on a polarization-modulated nulling ellipsometry. The new microscope employs a combination of scanning mirror and sample translation and thus enables high-throughput label-free detection of biomolecular microarrays with more than 10 000 protein or small-molecule targets. For illustration, we sho...

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