111In-LLP2A-DOTA Polyethylene Glycol–Targeting α4β1 Integrin: Comparative Pharmacokinetics for Imaging and Therapy of Ly...
Published in Journal of Nuclear Medicine
Molecular imaging of very late antigen-4 (α4β1 integrin) in the premetastatic niche.
Published in Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Despite advances in cancer treatment over the past few decades, metastatic disease remains the primary cause of morbidity and mortality. Recent reports suggest the formation of a "premetastatic niche" before the metastatic cascade, where niche is defined as the microenvironment for tumor cells to be able to engraft and proliferate at secondary site...
