Kit Lam Lab - UC Davis
  • Upload

  • Log in

  • Sign up

Search on MyScienceWork
News Publications Members

Publication search

Sort by
  • Relevance
  • Published Date

PEG-oligocholic acid telodendrimer micelles for the targeted delivery of doxorubicin to B-cell lymphoma.

Kai Xiao Luo, J Yuanpei Li Lee, Js Gabriel Fung Kit S. Lam

Published in Journal of Controlled Release

Doxorubicin (DOX) is one of most common anti-cancer chemotherapeutic drugs, but its clinical use is associated with dose-limiting cardiotoxicity. We have recently developed a series of PEG-oligocholic acid based telodendrimers, which can efficiently encapsulate hydrophobic drugs and self-assemble to form stable micelles in aqueous condition. In the...

A novel size-tunable nanocarrier system for targeted anticancer drug delivery.

Y, Li K, Xiao J, Luo J, Lee S, Pan Ks, Lam

Published in Journal of Controlled Release

We have developed a nanocarrier drug-delivery system based on micelles formed by a new class of well-defined linear PEGylated two-arm oligomer of cholic acids in aqueous solution. By varying the length of the linear PEG chains and the configuration of cholic acid oligomer, one can easily fine-tune the physicochemical properties of the amphiphilic p...

Powered by Polaris
  • About the Lab
  • Our Research
  • FAQ