A novel peptide inhibitor attenuates C-reactive protein's pro-inflammatory effects in-vivo.
Published in International journal of cardiology
Higher levels of C-reactive protein (CRP) predict cardiovascular events and also portend a poorer prognosis in patients with acute coronary syndromes. Much in-vitro and in-vivo data support a role for CRP in atherogenesis. Using the one-bead-one-compound (OBOC) combinatorial library method we have successfully identified peptides against human CRP ...
