Kit Lam Lab - UC Davis
  • Upload

  • Log in

  • Sign up

Search on MyScienceWork
News Publications Members

Publication search

Sort by
  • Relevance
  • Published Date

CD22-Binding Peptides Derived from Anti-CD22 Ligand Blocking Antibodies Retain the Targeting and Cell Killing Properties...

Pearson, David O’Donnell, Robert T. Cerejo, Miguel McKnight, Hayes C. Wang, Xiaobing Mařik, Jan Lam, Kit S. Tuscano, Joseph M.

Published in International Journal of Peptide Research and Therapeutics

CD22 is a B-cell specific membrane glycoprotein that mediates homotypic and heterotypic cell adhesion; it also regulates B-cell receptor (BCR)-mediated signals. Monoclonal antibodies (mAb) directed at the ligand binding domain of CD22 initiate CD22-mediated signal transduction and apoptosis in B-cell lymphomas (NHL). Amino acid analysis of the comp...

Powered by Polaris
  • About the Lab
  • Our Research
  • FAQ