A novel small molecule, LAS-0811, inhibits alcohol-induced apoptosis in VL-17A cells
Published in Biochemical and Biophysical Research Communications
One of the pathways by which alcohol induces hepatocyte apoptosis is via oxidative stress. We screened several chemically-synthesized small molecules and found LAS-0811, which inhibits oxidative stress. In this study, we elucidated its role in inhibiting alcohol-induced apoptosis in hepatocyte-like VL-17A cells. VL-17A cells were pre-incubated with...
