Macromolecular scaffolds for immobilizing small molecule microarrays in label-free detection of protein-ligand interacti...
Published in Analytical chemistry
We explored two macromolecular scaffolds, bovine serum albumin (BSA) and polyvinyl alcohol (PVA), as chemically complementary platforms for immobilizing small molecule compounds on functionalized glass slides. We conjugated biotin molecules to BSA and amine-derivatized PVA and subsequently immobilized the conjugates on epoxy-functionalized glass sl...
